Semax & Selank Nasal Spray Formats: Research Handling Guide

RESEARCH USE ONLY. Reference information for laboratory research materials. Not medical, dosing, or usage guidance; nothing here concerns human or animal use.

Semax and Selank are the two research peptides most commonly supplied in nasal-spray format — either as a pre-made multi-dose solution or as lyophilized material a lab prepares into a sprayer. Here is the handling reference for both routes.

Pre-made spray solutions

Store unopened in a cool, dry place away from light. After opening, refrigerate at 2–8°C and use within the appropriate window — multi-dose aqueous solutions are the least stable format a peptide ships in. Check the COA for the stated concentration (mg/mL) and confirm the lot number matches the bottle label.

Preparing a sprayer from lyophilized material

The math is simple but unforgiving: the concentration you mix determines what every pump actuation delivers. A metered nasal pump typically dispenses 0.05–0.13 mL per actuation (0.10 mL is the most common — the pump's spec sheet states the exact figure). Concentration (mg/mL) × pump volume (mL) gives the amount per actuation. Our free nasal spray calculator does the full computation — enter the vial amount, target amount per spray, and pump output, and it returns the exact solvent volume, total sprays, and resulting concentration, with a warning if the volume won't fit the bottle.

Add solvent slowly down the glass (never jetted at the powder), swirl gently until dissolved — don't shake — then transfer to the spray bottle.

COA checks specific to these compounds

Semax (MEHFPGP, ~813.9 Da) and Selank (TKPRPGP, ~751.9 Da) should each show mass-spec identity near the theoretical mass, HPLC purity with chromatogram, and a matching lot number. N-acetyl and amidated variants have different masses — the COA should name the exact variant tested. The COA checker walks the generic red flags.

NovaForge Labs is a sponsor of The Peptide Review — research-grade reference materials, every lot HPLC-tested with a published COA →

Frequently asked questions

How much does a nasal spray pump dispense?
Most metered nasal pumps dispense 0.05–0.13 mL per actuation, with 0.10 mL the most common. The pump's specification sheet gives the exact output, which determines the amount delivered per spray at a given concentration.
How are nasal spray research peptides stored?
Unopened solutions store cool, dry, and dark. After opening, refrigerate at 2–8°C and use within an appropriate window — aqueous multi-dose solutions degrade faster than lyophilized material.
How do you calculate concentration for a peptide nasal spray?
Concentration (mg/mL) equals the peptide amount divided by solvent volume; the amount per actuation equals concentration × pump output. A free nasal spray calculator solves for the solvent volume that hits a target amount per spray.